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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAM
All Species:
24.55
Human Site:
Y270
Identified Species:
60
UniProt:
P19021
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19021
NP_000910.2
973
108332
Y270
P
Q
L
P
Q
A
F
Y
P
V
G
H
P
V
D
Chimpanzee
Pan troglodytes
XP_001136726
972
108212
Y270
P
Q
L
P
Q
A
F
Y
P
V
E
H
P
V
D
Rhesus Macaque
Macaca mulatta
XP_001096156
907
101089
Y271
P
Q
L
P
Q
A
F
Y
P
V
E
H
P
V
D
Dog
Lupus familis
XP_536289
1243
137222
Y538
P
Q
L
P
Q
A
F
Y
P
V
E
H
P
V
D
Cat
Felis silvestris
Mouse
Mus musculus
P97467
979
109029
Y274
P
Q
L
P
Q
A
F
Y
P
V
E
H
P
V
D
Rat
Rattus norvegicus
P14925
976
108657
Y275
P
Q
L
P
Q
A
F
Y
P
V
E
H
P
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424857
666
74100
W53
Y
R
V
R
N
G
Q
W
T
L
I
G
R
Q
S
Frog
Xenopus laevis
P12890
875
97066
G262
H
G
K
W
T
L
I
G
R
Q
S
P
Q
L
P
Zebra Danio
Brachydanio rerio
XP_699436
1010
112189
Y273
P
L
L
P
Q
A
F
Y
P
A
T
N
T
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784943
883
95674
N266
T
H
N
D
E
M
C
N
L
Y
L
M
Y
Y
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
91.2
70.8
N.A.
90
89.6
N.A.
N.A.
51.1
60.2
55.7
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
99.6
92
73.9
N.A.
94
94.2
N.A.
N.A.
59.2
74.5
70.9
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
0
60
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
26.6
6.6
73.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
70
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
70
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
50
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
0
10
0
0
10
10
0
0
0
% G
% His:
10
10
0
0
0
0
0
0
0
0
0
60
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
70
0
0
10
0
0
10
10
10
0
0
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
10
0
0
0
10
0
0
0
% N
% Pro:
70
0
0
70
0
0
0
0
70
0
0
10
60
0
10
% P
% Gln:
0
60
0
0
70
0
10
0
0
10
0
0
10
10
0
% Q
% Arg:
0
10
0
10
0
0
0
0
10
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% S
% Thr:
10
0
0
0
10
0
0
0
10
0
10
0
10
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
60
0
0
0
60
0
% V
% Trp:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
70
0
10
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _